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Advertisement According to the carrying capacity, there are minivans (under 1.8 tons), light trucks (1.8-6 tons), medium goods vehicles (6-14 tons) and heavy trucks (over 14 tons). The general function of deacetylation with the lysine residues is carried out by HDAC enzymes. Apart from this pair of HDACs there exists another enzyme which performs a similar function. The name with this enzyme is SIRT1 also it removes the acetyl group by way of a very unique mechanism. The end product of this enzyme mediated reaction is nicotinamide. Removal of acetyl group by HDACs doesn't involve NAD+ hydrolysis. Inhibitors like trichostatin A, which show specific action against HDACs don't have any action against SIRT1. In 2017, the blockchain enters the public eye through bifurcation, CryptoKitties and ICO. Driven by investment opportunities and media attention, traditional businesses and consumers have begun to focus on the cryptocurrency and its underlying blockchain technology. Today, being in the blockchain is like engaging in more grandiose and socially valuable activities. That is why blockchain is emerging, many of which are sold out, and for many, the line between personal and professional interests is becoming blurred. He added: "austerity has failed and will only continue to undermine our economy in the brexit negotiations.